Natural Disasters & Epidemics

1721  Boston smallpox outbreak in Massachusetts Bay Colony killing 844 people   

1729  Measles in Thirteen Colonies   

1730  Yellow fever in Spain   

1732  influenza in Thirteen Colonies   

1733  smallpox in Canada, New France   

1738  Great Plague of 1738 in Balkans killing 50,000 people   

1738  Smallpox in Thirteen Colonies   

1739  Measles in Thirteen Colonies   

1743  Plague in Italy   

1747  measles in Thirteen Colonies   

1754  Benjamin Waterhouse, physician (smallpox vaccine pioneer)   

1755  smallpox in North America   

1759  Measles in North America   

1761  influenza in North America, West Indies   

1763  smallpox in North America, present-day Pittsburgh area.   

1770  Russian plague of 1770-1772 in Russia killing 50,000 people   

1770  smallpox in Pacific Northwest natives   

1772  Measles in North America   

1772  Persian Plague in Persia killing 2 million+ people   

1775  Influenza in England   

1778  dengue fever in Spain   

1780  north American smallpox epidemic in Plains Indians   

1788  Smallpox in Pueblo Indians   

1788  Measles in United States   

1789  smallpox in New South Wales, Australia   

1791  members of the French National Guard under the command of General Lafayette open fire on a crowd of radical Jacobins at the Champ de Mars, Paris, during the French Revolution, killing as many as 50 people.   

1793  yellow fever attacks Philadelphia, Pennsylvania, United States killing several thousand people   

1793  yellow fever attacks Philadelphia, Pennsylvania, United States, killing several thousand people   

1793  Influenza and epidemic typhus in United States   

1793  Yellow Fever Epidemic of 1793, resurgences in United States   

1796  First smallpox inoculation administered, by Edward Jenner   

1796  1st smallpox inoculation administered, by Edward Jenner   

1799  Edward Jenner's smallpox vaccination is introduced   

1800  Dr Benjamin Waterhouse gives 1st cowpox vaccination to his son to prevent smallpox   

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